Neutrophil Evolution and Their Diseases in Humans
نویسنده
چکیده
Granulocytes have been preserved and have evolved across species, developing into cells that provide one of the first lines of host defense against pathogens. In humans, neutrophils are involved in early recognition and killing of infectious pathogens. Disruption in neutrophil production, emigration, chemotaxis, and function cause a spectrum of primary immune defects characterized by host susceptibility to invasive infections.
منابع مشابه
Bats, viruses, emerging diseases and humans
This paper reviews the unique characteristics of bats, their important roles in providing ecosystem services, their viruses in relation to emerging diseases. Bats, as flying mammals, are the second largest order following rodents, with a wide variety (over 1400 identified species among 230 genera of 21 families in the world) due to their flying power and echolocation. Despite their importance a...
متن کاملAnti-Cardiolipin and Anti-Neutrophil Cytoplasmic Antibodies in Iranian Patients with Behcet's Disease
Background: The prevalence of anti-Neutrophil Cytoplasmic Antibodies (ANCAs) and anti-Cardiolipin Antibodies (anti-CL Ab) in Behcet’s Disease (BD) and also their roles in vascular involvement is controversial. Objective: To assess the prevalence of ANCAs and anti-CL Ab as well as their correlations with clinical manifestations in Iranian patients with BD. Methods: In this case/control study, th...
متن کاملThe Netosis Formation of HL-60 Cell Differentiated to Neutrophil-Like Cells by LPS
Background: Neutrophils are the most abundant white blood cells in humans. Recently, a novel strategy called the formation neutrophil extracellular traps (NETs) was described. NETs is a new strategy for pathogen response. This study focused on whether LPS induced NETs release in vitro in the HL60 cell line. Methods: In this study, the HL60 cell line was used for culture and DMSO for induction ...
متن کاملNeutropenia Following Intravenous Immunoglobulin Therapy in Pediatric Patients with Idiopathic Thrombocytopenic Purpura
Background: Children with idiopathic thrombocytopenic purpura who are treated with intravenous immunoglobulin therapy might experience a decline in their absolute neutrophil count. The aim of this study was to investigate the incidence of neutropenia following intravenous immunoglobulin therapy in children with idiopathic thrombocytopenic purpura undergoing intravenous immunoglobulin therapy. ...
متن کاملLice, Humans, and Microbes
Lice are small, wingless, minor ectoparasites of mammals and birds. More than 540 blood-sucking lice (Phthiraptera: Anoplura) have been described with each host having its own type of louse, suggesting the cospeciation of the lice species with their host. Among these, two lice species from two different genera infest humans: Pediculus humanus and Phthirus pubis (pubic “crab” l...
متن کامل